The games take place in a fictional universe in which a range of characters compete in fighting tournaments for prizes and bragging rights.
Ming Na - Chun Li
Bruce Greenwood - Captain Guile
Wade Williams - Sagat
B.D. Wong - Ryu
Troy Baker - Ken Masters
Richard White - M. Bison
Whilmer Vladarama - Vega
Andrew Kishno - Fei Long
Gary Anthony Williams - Balrog
Jennifer Hale - Cammy White
Mary Elizabeth McGlynn - Eliza Masters, Crimson Viper
Kevin Michael Richardson - E. Honda, Dee Jay, Birdie
Dee Bradley Baker - Blanka, Zangrief
Jonathan Adams - Akuma, Dhalsim
Lauren Tom - Sukara, Rose
Grey DeLisle - Sharon
Kari Wuhurr - Poison
Nome - Alaska
Moscow - Russia
Hawaiii - US
Sydney - Austrailia
Miami - Florida
Paris - France
Venice - Italy
Kenya - Africa
Madagascar - Africa
Hong Kong - China
Tokyo - Japan
M. Bison's base/ Berlin - Germany
Ryu vs. Ken (training) in Tokyo Japan
Chun Li vs. Cammy (Training) in Tokyo Japan
E. Honda vs. Birdie in Madagascar Africa
Balrog vs. Birdie in Kenya Africa
M. Bison: "At Last, I have found the secrets of Hong Gong, and will learn it's moves and become one of the most invincible of all Shadaloo, and the world!"
Ken and Ryu: "You know before Sensei passed, we defined our skills, and defined ourselves! Couldn't agree more!"
Chun Li: "Fighting does'nt make the warrior, it's the wisdom that makes the warrior!"
Crimson Viper: "Sheesh Cammy aren't you embarrassed having that oversized butt sticking out, aren't you at leased concerned it being compared to a Horse's Rear answer me, or are you blushing now!"
Akuma: "Bison, you arrogant coward, you think being Germany's former Nazi was lame, Shadaloo is alot lamer, the Power of Hong Gong, can only work for the bloodline of the Dyamyo!"