Sly Cooper: Path of the Cooper is the fifth sequel of Sly Cooper: Thieves in Time for the Playstation 3, Playstation 4, PS Vita, Xbox 360, and Xbox One Created by Brandon Mania Studios.
After the explosion of Le Paradox's blimp the gang members believe that Sly died. After that it shows a teaser image in which Sly was time traveled to Egypt. Now that the Cooper Gang has Sly back, they must recruit a big league of thieves and superheroes to defeat a new global threat.
- Sly Cooper (Kevin Miller), The Master Thief: Leader of the Cooper Gang.
- Bentley (Matt Olsen), The Brains/Demolition Expert:
- Murray (Chris Murphy), The Brawn/Getaway Driver:
- Carmelita Fox (Grey DeLisle), Marksman: Sly's wife and former Interpol Inspector she live in her apartment were Sly see her again she give him a cell phone to call her. In the end she stays with the cooper gang and got married to Sly.
- Guru (Terry Rose), Mystic: Murray's teacher from the events of Sly 3: Honor Among Theives.
- Panda King (Kevin Michael Richardson):A former member of the Fiendish Five.
- Dimitri (David Scully), Frogman:
- Riley (Tom Kenny) He is the newest member of the cooper gang, a squirrel, who can weild a similar weapon to Sly's cane(its like a sword) and have different and similar game mechanics to Sly as well. He is an archeologist in Paris who was taking his friend Hanna out for dinner, but was attacked by ninjas and kidnapped his girlfriend. he believes that a cooper necalce he has is the reason for their attack, and wants to help Sly but also get his friend back.
- Vincent (John DiMaggio), 2nd Brawn: An American alligator who's an old friend from Murray's childhood during elementary school. He goes by his ring name, "The Vincigator", as he works in a professional wrestling league since college. He joined the Cooper Gang as the 2nd muscle for the job and wears a similar outfit as Murray's. In the end he & Mz. Ruby got married in her Haitian family renuinion with her sister. He also holds a grudge against Carmelita for getting his father arrested when they were in middle school and frequently butts heads with Sly over wether or not she is a friend or a foe to the gang.
- Jimmy (Tara Stong), Apprentice: A kind hearted and bright young gecko from the town of Sunset Springs who became an orphan after Chairman Weaver took over the town and killed his parents for protesting. He came to idolize Sly and his gang following their victory over Muggshot in the first game and has dreamt of joining them for years. When the gang is confronted by Jonathan, he passionately defends the gang and says that Sly is not just a thief, but a hero. He is later adopted by Sly.
- Chan Poa (Eric Bauza), Martial Arts Expert: Panda King's new student after joining the gang. He is a Chimpanzee.
- Felicia Sparks (Jennifer Hale): Bentley's new love interest who is a pro racer. She's a cheetah and she's sassy. She joined the team to replace Penelope. In the end she & Bentley begin their relationship on the racing circuit.
- Mz. Ruby (Prescilliana Esparolini): Vincent's love interest and a former member of the Fiendish Five. After Sly defeated her in Haiti and Carmelita sent her to jail, she remained imprisoned for five years, during which she got back into shape, until she was paroled for good behavior and became a dedicated environmentalist. When Bentley tells the gang they need her, Sly is quick to object, but Vincent tells the Gang that Ruby isn't as bad as she looks, explaining he met her on a visit to Haiti as a child and befriended her, causing her to develop a massive crush on him.
- The Grizz (Fred Tatasciore): Who befriended Dimitri as they both love art and music and later joined the team.
- Webslinger(Eric Lopez): A young 4 eyed former circus acrobat from Mexico. When it comes to acrobatics, he's exactly like Sly. He can climb on walls, swing in webs attached to the house and make traps for guards to get stuck in. He's a black tarantula and the nephew of the Contessa.
- Brandon Frangipani (voiced by himself): The new member of the Cooper gang and the first human in the Sly Cooper series. He is a superhero named Brandon Mania.
- William Veil/Ironsides (Eric Roberts (first form)/James Spader (final form): The true antagonist of the game, and Clockwerk's biological AI (Artificial Intelligence) son. He will appear in the secret final episode once a player completes all missions and side missions.
- Drako (Clancy Brown): The Leader of the Syndicate and the semi-main antagonist. Drako was born in an unknown origin. He's a red European Dragon that wants to rule the world on the next planetary alignment to move across time and remake the world in his image and releasing his dragon kind using the Legacy stones. He shows superiority and leadership. In the end Sly & his ancestors defeated him, and he ultimately fell to his death along with his dragon brotheren entirely.
- Alduin (Tim Curry): One of Drako's brothers and the secondary main antogonist. He's a black European Dragon that was sealed within a sarcophagus along with his remaining brothers.
- Shavax (Fred Tatasciore): One of Drako's brothers and a supporting antagonist. He's a dark brown European Dragon that was sealed within a sarcophagus along with his remaining brothers.
- Sardon (Steven Blum): One of Drako's brothers and a supporting antagonist. He's a blue European Dragon that was sealed within a sarcophagus along with his remaining brothers.
- Fyold (Nolan North): One of Drako's brothers and a supporting antagonist. He's a green European Dragon that was sealed within a sarcophagus along with his remaining brothers.
- Handrim (Dave Fennoy): One of Drako's brothers and an anti-hero. He's a white European Dragon who was against Cadmus's plan of world conquer and rebelled against him.
- Trudge (Mark Dindal): Drako's personal bodyguard who is a loyal cougar.
- Hex Alucard (Peter Stormare): A shadowy Romanian vampire bat. Hex is a powerful sorcerer; who is a lot older than he looks. Being more than 500 years old, Hex has been using a special body transference ritual for over 5 centuries to keep himself alive. He originated in 15th century Transylvania; once a holy priest, he accidentally caught The Plague from a group of children. Hex knew he would soon die within an hour when his secret admirer decided he was too handsome for her to lose, and transformed him into a vampire. Cursed to forever live on as a blood sucking creature of the night, Hex as lived for 500 years and has let the darkness completely take him over. He turns innocent victims into his loyal minions. He was awakend in the present day by Cadmus and joined the Syndicate. Like the Contessa, Hex has the power of hypnosis.
- Estaban Vivero (Lewis Black): A wrestling manager and a scorpion, Estaban created a poison to help his wrestlers cheat in the ring, but was arrested for it, and is now an manager of an illegal underground wrestling court known as "The Sting Ring".
- Weaver (Dee Bradley Baker): As a young street urchin, he lived in a bad neighborhood with no family to help him not even the sheriff. as he grew he couldn't take this life anymore so he wanted revenge on the whole Town by being elected as Chairman. He's a cruel, aggressive, short-tempered western Diamondback Rattlesnake who runs a western town.
- Mz. Trudy (Cree Summer): Mz. Ruby's jealous and psychotic twin sister. Unlike her sister, Trudy is thinner and more attractive. Her sister was always their mother's favorite because Trudy was spending more time on music voodoo instead of doing real voodoo as a child. She was beaten by Murray in the episode "Rivalry Vodooo".
- Axel Dasher (David Kaye): A notorious crime boss and pro-racer on the Monte Carlo racing circuit. He’s a fierce Jaguar who owns his own crime ring in Monte Carlo and all of Monaco but is mainly stationed in Monte Carlo. In his old days, he was just a rookie street racer, challenging anyone and everyone he could find on the late night racing strips of Rio. Pretty soon he made a name for himself in racing and made it in a few pro matches. However, due to his over confidence and lack of mercy, he was targeted by the mob who control the more "seedier sections" of the racing world and was lead to a tragic accident, leaving him scarred for life as well as having his title stolen from him. Soon after, he lead his own virtually unchallenged racers. However, his league was under the constant interference of a rival female racer, Felicia Sparks. Although he’s incredibly smart and a genius mechanic, he's no honorable racer and always looks for opportunities to cheat on the track. He owns a fancy Hotel/Resort and Casino called "Racing Aces".
- Cornelious Nexus (Pat Fraley): A highly intelligent and crafty genetic scientist and a master of quantum and temporal physics. This insidious Nile crocodile was taught by Dr.M as a young croc and knows all about genetic mutation and gene splicing. He’s a well-respected genius in the average community, but behind closed doors, he’s a maniacal mad scientist who conducts immoral and insane experiments on whomever he can get as a test subject.
- El Jefe (Nolan North): He returns for revenge on Sly Cooper for locking him up in prison as he was recruited by Cadmus.
- Penelope (Annette Toutonghi): Bentley's ex-girlfriend. Later in the game, she admitted her reasons behind her actions in Thieves in Time was because of her anger towards Sly for "abandoning" the gang in Honor Among Thieves to be with Carmelita and leaving her and Bentley to continue his work.
- The Infinity Master (Brandon Frangipani; cameo): The Infinity Master makes a brief cameo at the end of the game, possibly hinting at a sixth installment.
- Jonathan "John" Sheppard (Troy Baker): Interpol's new Inspector and Carmelita Fox's replacement. He's a German Sheppard
- Commisioner Jones Monitor (Jim Meskimen): Johnny's partner. He is a Moniter Lizard.
- Roger (Patrick Warburton): a bumbling Rhino who always seen doing wrestling with Murray.
- Lt. Gronk (Richard McGonagle):
- The Maka Kong (S. Scott Bullock): A gorilla wrestler who used to work with Vincent.
- Big Nelson (J.B Blanc): Weaver's right-hand man, who is a brutish Gila monster who carries two revolvers and a gattling gun.
- Sheriff Red (Eric Roberts): The Sheriff of the small town Cole lives. He's a red-tailed hawk.
- Don Octavio (David Scully): Freed from jail to do community service and still likes to do opera. Seen during the Monte Carlo Grand Prix and looks a little younger from his last encounter with the Cooper gang. Thought to be in prison until he was freed for community service by helping the elderly and entertaining them with his opera singing. He's now a traveling aristocrat.
- Ms. Decibel (Eliza Jane Schnieder): Now a traveling aristocrat.
- The Bobby Bros: Three different Booby brothers similar to Ed, Oly and Waddle from Sitting Ducks. They were Axel's lazy henchmen and were later fired from the job. They chose to be aristocrats and later became allies of the Cooper Gang since the 4th episode.
- Dan (Louis Chirillo): The 1st brother who wears a blue tropical shirt, and speaks with a New York accent. He's a Blue-footed Booby. During parties, he wears a blue suit jacket, and a blue top hat.
- Hector (Phil Hayes): The 2nd brother who wears a red waistcoat, a lavender beret, spits on his feet and speaks in a Beatnik accent. He's a Red-footed Booby. During parties, he wears a red suit jacket and a red fedora with a feather.
- Fred (Rob Paulson): The 3rd brother with a little overweight appearence. He wears a green bowtie, and a shirt with glasses. He's a Green-footed Booby. During parties, he wears a green suit jacket and a green bowler hat.
- Tobio Tokioka (George Takei): A Japanese racer that participated in this year's Brazilian Grand Prix and is Japan's representative. He's a japanese Maqacue.
- Miguel Revira (Carlos Alazraqui): A Mexican racer that participated in this year's Brazilian Grand Prix and is Mexico's representative. He's a Mexican bear.
- Guido Calvino (Daran Norris): An Italian racer that participated in this year's Brazilian Carlo Grand Prix and is Italy's representative. He is an Italian Wall Lizard.
- Bernando Garcia (Christain Lanz): A Brazilian racer that participated in this year's Brazilian Grand Prix and is Brazil's representative. He is a blue and yellow Macaw.
- Tyson Conrad (Phil LaMarr): A Jamaican racer that participated in this year's Brazilian Grand Prix and is Jamaica's representative. He is a Jamaican Boa.
- Nigel Hamilton (Simon Baker): An Australian racer that participated in this year's Brazilian Grand Prix and is Australia's representative. He is a Red Kangaroo.
- Joseph (Brian George): An Indian racer that participated in this year's Brazilian Grand Prix and is India's representative. He is a Clouded Leopard.
- Cain Prost (Jeffrey Garcia): A Spanish racer that participated in this year's Brazilian Grand Prix and is Spain's representative. He is a Spanish Salamander.
- Mikey (Danny Jacobs): A Chameleon and vigilante.
Each member of the Syndicate has guards to suit the environment.
- Water Buffalos: Flashlight guards
His henchmen are desert type reptiles. Some of them are gunslingers.
- Frilled Lizards:
- Leopard Lizards:
- Bearded Dragons: flashlight guards
Mostly hired thugs as guards
- Emperor Tamarins: Carry clubs, broken bottles and megaphones.
- Nazca Boobies:
- Giant Anteaters: Flashlight Guards.
- Blue Spotted Newts:
- Poison Dart Frogs:
- Cuban and Mugger Crocodiles: flashlight guards
His henchmen are resurrected dragons and other reptiles.
- Rooftop Guards: Ice Dragons and Earth Dragons
- Komodo Dragons:
- Chinese Water Dragons:
- Clockwerk Sentries:
- A Fierce Showdown Royale: The Cooper Gang are going to Mexico City, Mexico to see Murray's old friend named Vincent.
- Venom in the Ol' West: The Cooper Gang are going to Texas to a small town home state to face a rattlesnake known as Weaver.
- The Fast and the Ferocious: Sly and his gang are going enter the race to face a jaguar named Axel, who owns the racing circuit.
- Rivalry Voodoo: Vincent tells the gang about his girlfriend Mz. Ruby, which comes as a shock to Sly. They are to face Mz. Ruby's sister.
- Romania of Blood: The Cooper Gang are going to Romania.
- Tick Tock…BOOM: Bentley gets a weird mail, which tells the gang to go to Clockwork's old hideout. After he showed the gang the mail, his computer explodes. So the gang leave for Russia, only to see that the place is back online.
- A Darkened Past: The Cooper Gang have defeated Drako, but they must depart to William's underground city, but Sly learns more about why his parents died on that horrible night.
- Prelude : Sly is stuck in ancient Egypt, with Slytunkhamen Cooper II ready to create the Theivious Racoonus. Sly has an idea to contact his friends. The Cooper Gang are off to find him.
- Mexico City, Mexico
- San Antonio, Texas
- Monte Carlo, Monaco
- Moscow, Russia
- Transylvania, Romania
- Port Sudan, Sudan
- United States
- Krack-Karov Volcano, Russia
- City of the Damned, Paris, France