In a trip to Hong Kong, the gang head off for a trip, but things get out of hand when an evil Chinese sorcerer returns as a warning to China.
- Scooby-Doo (Frank Welker)
- Shaggy Rogers (Matthew Lillard)
- Fred Jones (Frank Welker)
- Daphne Blake (Grey DeLisle)
- Velma Dinkley (Mindy Cohn)
- Fei Chi (Kim Mai Guest) - befriends Shaggy and Scooby
- Jiang Shi the Sorcerer (Keone Young) - a sorcerer with long white hair, a white mask with black and red stripes, and yellow uniform, he has the power to steal the Chi out of any living soul.
- Fei Sai (Kelly Hu) - Chi's paralyzed mother, she wears braces around her legs to walk, Reason: she knows the history of Jiang Shi.
- Pong Qai (James Hong) - the Minister of Justice, who has nothing to do with sorcery, Reason: He seems to be a superstious man.
- Fei Kai (James Sie) - a very gruff, yet arrogant business man, who is Sai's husband and Chi's father, Reason: because of his secret compartment in the basement.
- Old Man Kong (Keith Ferguson) - a mysterious, yet ill old man, who is dying from Leukemia, Reason: he seems not to have any leukemia in his record.
- Pong Qai/ Old Man Kong (James Hong and Keith Ferguson) - Reason: was using the Jiang Shi to scare off the newcommers from seeing that he stole the lost Goblet of the Emperor.