When a student always arrives late, his principle transfers to a school full of monster teens.
- Tyler Branch (Andrew Garfield) - the student transfered to Horror High, in the end, decides to stay, and be a full time student!
- Erzebet Dracula (Emma Stone) - a vampire who falls in love with Tyler, in the end, becomes Tyler's tutor and became officially Boyfriend & Girlfriend!
- Franks (Tom Hardy) - a frankenstein who is part of Tyler's new class, in the end, becomes Tyler's friend and helps out when there's bullying!
- Tutt (Rami Malek) - a mummy who is part of Tyler's new class, in the end, no longer feels nervous, and scared!
- Cheri (Monique Coleman) - a werewolf who is part of Tyler's new class, in the end, gets a crush on Franks!
- Bridgett (Emily Blunt) - a witch who has no long nose, and is part of Tyler's new class, in the end, Learns a lesson of Humility!
- Bryce (Edi Gathegi) - a invisible teen who is part of Tyler's new class, in the end, ends up getting a detention for framing Tyler at Lunch!
- Swampy (Channing Tatum) - a creature from the black lagoon, and is part of Tyler's new class, in the end, catches Bryce, and ends up going to College!
- Fiona (Amanda Bynes) - Swampy's girlfriend, has a tail of a mermaid, and is part of Tyler's new class, in the end, Also goes to college!
- Mr. Don Bones (Mark Hamill) - a skeleton teacher, who is Tyler's school teacher, in the end, gives Tyler the next year schdule
- Mrs. Headless (Carla Gugino) - the headmistress of the school, and is always headless, and rides on her horse, shares the same tone as Dr. Vera Gorski from Sucker Punch, in the end, awards Tyler student of the year, and still can't belive her head is gone when Tyler gave her a mirror!
- Count Dracula (Peter Stormare) - Erzebet's father who does approve of a human, in the end, faces Boogey-Man Jones and places him in the Pandora Box!
- Lillith Dracula (Marina Sirtis) - Erzebet's mother and Dracula's wife, who seems to like Erzebet to be in love with Tyler, in the end, makes Tyler a semi bite mark incase to become a vampire!
- Boogy-Man Jones (Hugo Weaving) - the main antagonist, plans to make the High School into a Paranormal castle to help him create avast Nightmares, in the end, was sent into Pandora's Box for punnishment!